(210123) -- PECHINO, 23 gennaio 2021 (Xinhua) -- UN membro dello staff controlla l'impostazione dei parametri sul bioreattore utilizzato per la coltivazione di cellule vero presso il laboratorio di soluzione di stock di vaccino COVID-19 durante l'operazione di prova presso Sinovac Life Sciences Co., Ltd. A Pechino, capitale della Cina, 15 luglio 2020. Alla fine del 2019, il nuovo coronavirus emerse e si diffuse rapidamente in tutto il mondo. Decine di milioni di persone sono state infettate. Gli scienziati hanno isolato il virus dai pazienti e hanno chiamato il virus COVID-19. Mentre il coronavirus rovina il mondo, il vaccino è diventato una speranza per l'umanità di vincere la pandemia. Sci
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(210123) -- BEIJING, Jan. 23, 2021 (Xinhua) -- A staff member checks parameter setup on the bioreactor used for Vero cell cultivation at the COVID-19 vaccine stock solution workshop during trial operation at Sinovac Life Sciences Co., Ltd. in Beijing, capital of China, July 15, 2020. In late 2019, the novel coronavirus emerged and rapidly spread across the world. Tens of millions of people have been infected. Scientists isolated the virus from patients and named the virus COVID-19. As the coronavirus wreaks havoc on the world, vaccine has become a hope for humanity to conquer the pandemic. Scientists cultivated the virus at Vero cells and selected a toxic strain suitable for making COVID-19 vaccine, namely CZ strain. By far, many people have been inoculated with inactivated vaccines against the virus. Here are some detailed production processes of China's inactivated COVID-19 vaccine. The production of the inactivated vaccine contains six steps: cultivation, inactivation, purification, formulation, filling and packaging. The first step is to replicate large amounts of coronavirus. Scientists inject the virus into an airtight bioreactor full of Vero cells which are isolated from African Green Monkey kidney cells. Continuous Vero lineage cells can be replicated through many cycles of division and not become senescent. The coronavirus replicates itself rapidly in Vero cell culture. Those viruses are then sent through an airtight pipe into another bioreactor in which a kind of inactivator is used for inactivation. Hours later, viruses totally lose pathogenicity and the ability to replicate. They become a pool of inactivated viruses. The inactivated virus pool is then taken to the purification zone where the inactivator and other impurities will be removed. The leftover is vaccine stock solution. The stock solution will then be mixed with adjuvant and diluent at an appropriate proportion. The mixture is called a semi-finished product, which will be stored in cold sto
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