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Ayer's Ague Cure Is Warranted To Cure All Malarial Disorders. Ayer's Ague Cure, which claims to neutralize "malarial poison, and expels it from the system." Visual motif: Tropical setting, a woman administering Ayer's Ague Cure to a man; both wearing Spanish style clothing. James Cook Ayer (May 5, 1818 - July 3. 1878) was the wealthiest patent medicine businessman of his day. He studied medicine and graduated from the medical school of the University of Pennsylvania. He never practiced medicine, but devoted his principal attention to pharmaceutical chemistry and the compounding of medicines. Much of his success was due to his advertising, and he published annually an almanac, 5, 000, 000 copies of which were gratuitously distributed each year. He died in an asylum in 1878 at the age of 60.
